Biacore (a Cytiva brand) is a leading company in the development, manufacture and marketing of innovative chip-based technology and products applied for detection and monitoring of biomolecular binding.
These systems, used in the drug discovery industry, life science research and the food analysis markets, allow you to observe a biomolecular interaction at the very moment it is taking place.
Using critical parameters that are typical for each interaction event, this chip-based technology is capable of identifying the nature of complicated biomolecular interactions (protein-protein, protein-DNA and protein-RNA interactions) with even very small molecules, displaying the progress of binding between specific molecules in real time, accurately reflecting the amount of material bound, and displaying the time course for each biomolecular binding.
It was recently documented that compounds bound by the sensor chip can be further eluted and be subjected to mass spec analysis. These capabilities are also relevant for small molecules, which cannot be easily detected and monitored by other known methodologies. Thus, Biacore users can find out how specifically two molecules bind to each other. Biacore users can also measure how fast the interaction takes place, and further study how strongly the examined molecules bind to each other. In addition, this technology enables to study the number of molecules involved in a given binding event.
For more details please visit: Biacore
